M. M. Manasi is a playback singer trained in Hindustani Vocal. She has sung more than 70 songs in Tamil, Telugu, Kannada, Malayalam, Hindi and English. She completed her studies at School of Management D.G. Vaishnav College. Her hits in Tamil – "Thamizachi" in Aarambam, "Kattikeda" in Kakki Chattai, "Semma Mass" in Mass, "Robo Romeo" in Tamizhuku En Ondrai Azhuthavum, "Sottavaala" in Puli, "Aatakari maman ponnu" in Ilayaraja's 1000th film Tharai Thappattai.
Manasi was born to Tamil speaking parents in Chennai and grew up in Mumbai. At the age of 2 she started learning music, her first public performances were bhajans sung during Navratri and Ganpati [Puja (Hinduism)|pooja]]s. She has a sister, M. M. Monisha.
Manasi was introduced by Ilaiyaraja to the Kannada music industry for the movie Drishya and by Vidhyasagar in Malayalam for Oru Indiya Pranayakadha. She made an entry into Bollywood with "Daddy Mummy" in Bhaag Johnny for music director Devi Sri Prasad. This song has 20 million views on YouTube.
Apart from singing, Manasi has also done voice acting for the leading heroines in the Tamil film industry: Baahubali, Thozha, Dharmadurai, Devi, Kaththi Sandai for Tamanna Bhatia, Maari for Kajal Agarwal, Anjaan for Samantha, Kamalinee Mukherjee in Iraivi, Meaghamann for Hansika Motwani, Darling and Velainu Vandhutta Vellaikaaran for Nikki Galrani, Tamizhuku En Ondrai Azhuthavum for Bindhu Madhavi, Vai Raja Vai for Tapsee, Yaan for Thulasi, Idharkkuthane Aasai Pattai Balakumara for Swathi, and Thirumanam Enum Nikkah for Nazriya.
Manasi has sung in Telugu and has many charting songs to her credit like "Bhelpuri" in Aagadu, "Notanki" in Power, "Private party in Sarrainodu", "Gunde Aagi Pothande" in Shivam, "Meenakshi" in Masala, "Om Sarvani" in Legend, "Mara O Mara in Tadakha", "Lucky Lucky Rai" in Balupu, and "Rangamma Mangamma" in Rangasthalam.